TECH OFFER

A Quorum Sensing Inhibitor Biosensor, Method and Use Thereof

TECHNOLOGY OVERVIEW

The present invention relates to a quorum biosensor. More particularly, the present invention relates to a biosensor for use in detecting short chain N-acyl homoserine lactone synthase inhibitor, characterized in that, the biosensor is a N-acyl homoserine lactone-producing Escherichia coli comprising an arabinose-dependent expression plasmid, its method of manufacturing and method of use thereof. The present invention provides a novel approach for development of short chain N-acyl homoserine lactone synthase inhibitor biosensor that is capable of detecting specific compounds, in particular non-antibiotic compounds, which can be used in controlling quorum sensing-mediated bacterial infection.

Mega - Trends

Healthcare

Technology Readiness Level (TRL)

TRL 2

Patent Number

UI 2016702117

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Contact person for this offer:

ChM Dr. Lee Ching Shya, PhD (Dual), RTTP

Technology Transfer Manager

Email: leecs@um.edu.my

Tel: +603-7967-7351/ 013-2250151

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