Bio-model comprising a fluid system and method of manufacturing a bio-model comprising a fluid system

A bio-model for simulating a surgical procedure comprises a synthetic anatomical structure which has a cavity. A fluid system is coupled to the cavity. In one embodiment the fluid system allows fluid to be pressurized. In one embodiment, the fluid system allows fluid to flow through the cavity. The bio-model may be manufactured based on medical image data using three-dimensional printing.